Thermo Fisher Scientific GTF2B Polyclonal Antibody
Rabbit polyclonal antibody against human GTF2B (TFIIB). Suitable for Western blot applications. Validated for multiple species reactivity. Supplied as a liquid, antigen affinity purified, and stored at 4°C or -20°C. For research use only.
- 카탈로그번호
- PA529812
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 72–292 of Human TFIIB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547286 |
Product Specific Information
- Recommended positive controls: HeLa, HeLa nuclear extract, Jurkat, Raji, NCI-H929
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (97%), Xenopus laevis (97%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ubiquitin is a 76 amino acid, highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. This posttranslational modification regulates the concentrations of key regulatory proteins by limiting their lifespans. Polyubiquitination involves activation by E1, transfer to E2, and covalent linkage to the target protein directly or via E3 ligase. Deubiquitination enzymes reverse this process. Ubiquitin tagging is involved in numerous cellular processes, including cell cycle, growth, differentiation, apoptosis, signal transduction, DNA repair, transcription regulation, transport, stress responses, immune response, and nervous system functions.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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