Thermo Fisher Scientific Carbonic Anhydrase IV Monoclonal Antibody (310413)
Carbonic Anhydrase IV 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, IP에 사용 가능. 인간 시료 반응성, Protein A/G 정제, Lyophilized 형태. 교차 반응이 낮고, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 8–25 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 310413 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Carbonic Anhydrase IV/CA4 (Ala19–Lys283) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609169 |
Product Specific Information
- In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human (rh) CA1, rhCA2, and recombinant mouse CA4 is observed.
- This antibody does not cross-react with rhCA3, 8, 9, 10, 12, 13, or 14.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They are involved in processes such as respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
This gene encodes a glycosylphosphatidyl-inositol (GPI)-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is unknown, but it may play a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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