Thermo Fisher Scientific SAPK4 Polyclonal Antibody
SAPK4(MAPK13) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB 및 IHC(P)에서 사용 가능하며, Human, Mouse, Rat에 반응. 항원 친화 크로마토그래피로 정제, -20°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human mitogen-activated protein kinase 13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2636006 |
Product Specific Information
The antibody detects endogenous levels of total MAPK13 protein.
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines. Activation occurs via phosphorylation by MAP kinase kinases or autophosphorylation triggered by MAP3K7IP1/TAB1 interaction. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, suggesting roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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