Thermo Fisher Scientific GCP4 Polyclonal Antibody
TUBGCP4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간 및 마우스 시료에서 반응하며, 고순도의 Affinity chromatography 정제 제품입니다. PBS/glycerol buffer에 보관하며 연구용으로 사용됩니다.
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- PA5101601
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카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TUBGCP4 (Accession Q9UGJ1), corresponding to amino acid residues H193–L243 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851035 |
Product Specific Information
This antibody detects endogenous levels of total TUBGCP4.
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the associated proteins GCP2, GCP3, GCP4, GCP5, and GCP6, which are essential components of microtubule organizing centers. These components localize to both the centrosome, where they contribute to microtubule nucleation, and the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed.
GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a 667-amino-acid protein that localizes to the metaphase spindle during mitosis. Upon proteasome inhibition, GCP4 accumulates at the pericentriolar material, where it participates in microtubule organization and nucleation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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