Thermo Fisher Scientific ORC6 Monoclonal Antibody (3A4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunoprecipitation (IP)

Assay-dependent

-

ChIP assay (ChIP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

3A4

Immunogen

Full length protein (Human): ORC6L if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ORC6,uniProtId:Q9Y5N6-1,ncbiNodeId:9606,antigenRange:1-252,antigenLength:252,antigenImageFileName:MA5-17022_ORC6_Q9Y5N6-1_Rat.svg,antigenImageFileNamePDP:MA5-17022_ORC6_Q9Y5N6-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538494

Product Specific Information

MA5-17022 reacts with ORC6 in human samples.

MA5-17022 has been successfully used in ChIP, immunoprecipitation and Western blot applications.

The MA5-17022 immunogen is ORC6 (hsORC) produced in P3-x63Ag.8.653 cells.

Target Information

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.