Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI3A3), TrueMAB
인간 OAS2 단백질(aa 60-335)에 특이적인 마우스 단클론 항체. Western blot에 최적화되어 있으며, 무보존제 동결건조 형태로 제공. 재구성 시 1 mg/mL 농도로 사용 가능. 연구용으로 바이러스 감염 관련 면역반응 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 60–335 of human OAS2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The OAS2 gene encodes a member of the 2-5A synthetase family, essential for the innate immune response to viral infection. The encoded protein is induced by interferons and catalyzes the synthesis of 2’,5’-oligoadenylates from ATP. These molecules activate RNase L, leading to viral RNA degradation and inhibition of viral replication.
Three known members of this gene family are clustered on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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