Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI3A3), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The OAS2 gene encodes a member of the 2-5A synthetase family, essential for the innate immune response to viral infection. The encoded protein is induced by interferons and catalyzes the synthesis of 2’,5’-oligoadenylates from ATP. These molecules activate RNase L, leading to viral RNA degradation and inhibition of viral replication.
Three known members of this gene family are clustered on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.