Thermo Fisher Scientific CCR10 Monoclonal Antibody (6E3E4)
CCR10 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. 인간 시료 반응성 확인됨. 단백질 G 정제, PBS 버퍼 및 sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E3E4 |
| Immunogen | Purified recombinant fragment of human CCR10 (AA: extra mix) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090724 |
Target Information
Chemokines are small (approximately 8–14 kD), mostly basic, structurally related molecules that regulate leukocyte trafficking via 7-transmembrane, G protein-coupled receptors. They play key roles in immune system development, homeostasis, and function, and affect central nervous system cells and endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into two major subfamilies, CXC and CC, based on the arrangement of conserved cysteine residues: separated by one amino acid in CXC, adjacent in CC.
CCR10 is the receptor for CCL27; CCR10–CCL27 interactions are involved in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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