Thermo Fisher Scientific PTPN1 Monoclonal Antibody (OTI1A2), TrueMAB
PTPN1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow cytometry에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer(pH 7.3, 8% trehalose) 기반. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human PTPN1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase involved in regulating the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK, inactivating its kinase activity. PTP1B is also implicated in CKII- and p60c-src-induced signaling cascades and regulates EFNA5-EPHA3 and MET signaling pathways, influencing cell reorganization and growth factor responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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