Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI2G5), TrueMAB
인간 ESRRA 단백질(aa 206-417)을 항원으로 한 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 검증됨. 무보존제, 동결건조 형태이며 1 mg/mL 농도. 연구용으로 대사 조절 관련 ESRRA 단백질 분석에 적합.
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Applications
- Western Blot (WB): Tested at 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 206–417 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan nuclear hormone receptor. ERR family members share a highly conserved DNA-binding domain with 68% amino acid identity to the estrogen receptor. ERRα binds to an ERRα response element (ERRE) containing the consensus half-site 5'-tnaaggtca-3' and interacts with the MCAD response element NRRE-1, acting as a regulator of MCAD promoter activity. ERR1 is implicated in metabolic regulation and is highly expressed in tissues that preferentially metabolize fatty acids. The corresponding gene is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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