Thermo Fisher Scientific Nkx3.1 Monoclonal Antibody (UMAB195), UltraMAB
인간 NKX3-1 단백질을 인식하는 마우스 단클론 항체로, IHC, ChIP, Peptide Array 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 전립선 특이적 종양 억제 인자 연구용으로 최적화.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | - |
| ChIP assay (ChIP) | Assay-Dependent | - |
| Peptide Array (Array) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB195 |
| Immunogen | Full-length human recombinant protein of human NKX3-1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
NKX3-1 is a homeodomain-containing transcription factor and a putative prostate tumor suppressor. It is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is commonly observed in human prostate carcinomas and prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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