Thermo Fisher Scientific Phospho-AMPK alpha-1 (Ser485) Polyclonal Antibody
Phospho-AMPK alpha-1 (Ser485) 폴리클로날 항체로, 인간, 생쥐, 닭, 원숭이, 랫트에 반응합니다. Western blot에 1:1,000 희석 비율로 사용 가능하며, AMPK 신호전달 연구에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer485 of human AMPKα1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 21 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10978464 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with phosphorylated AMPK-alpha2 or other related proteins.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein.
Through this mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes and has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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