Thermo Fisher Scientific ESAM Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human ESAM. Recombinant protein control fragment (Product #RP-106323). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ESAM,uniProtId:Q96AP7-1,ncbiNodeId:9606,antigenRange:132-209,antigenLength:390,antigenImageFileName:PA5-111324_ESAM_Q96AP7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111324_ESAM_Q96AP7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856734

Product Specific Information

Immunogen sequence: DKQGKSRGHS IKTLELNVLV PPAPPSCRLQ GVPHVGANVT LSCQSPRSKP AVQYQWDRQL PSFQTFFAPA LDVIRGSL

Target Information

ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.