Thermo Fisher Scientific ETV5 Polyclonal Antibody
ETV5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 면역세포염색(ICC/IF)에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보관. 인간 시료에 반응하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ETV5. Recombinant protein control fragment (Product #RP-105253) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662848 |
Product Specific Information
Immunogen sequence:
AAGPVQGVGPA PAPHSLPEPG PQQQTFAVPR PPHQPLQMPK MMPENQYPSE QRFQRQ
Sequence identity:
Highest antigen sequence identity to the following orthologs – mouse 93%, rat 93%.
Target Information
ETS variant 5 (ETV5) is a transcription factor of the ETS family, a divergent member of the winged helix-turn-helix superfamily. It is expressed in brain, placenta, and other tissues involved in development.
Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, leading to progressive germ cell depletion in affected mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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