Thermo Fisher Scientific IFNAR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL

-

Immunocytochemistry (ICC/IF)

5-20 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein Interferon Alpha/Beta Receptor 2. The antigen corresponds to amino acid range 27-243 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IFNAR2,uniProtId:P48551-1,ncbiNodeId:9606,antigenRange:27-243,antigenLength:515,antigenImageFileName:PA5-119217_IFNAR2_P48551-1_Rabbit.svg,antigenImageFileNamePDP:PA5-119217_IFNAR2_P48551-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2903715

Target Information

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.