Thermo Fisher Scientific CCRD6 Polyclonal Antibody
Thermo Fisher Scientific의 CCRD6 Polyclonal Antibody는 마우스 베타 케모카인 수용체 D6를 인식하는 염소 유래 IgG 항체입니다. IHC, Flow Cytometry, ELISA에 적합하며, 고희석에서도 우수한 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 |
| Flow Cytometry (Flow) | 1–5 µg/mL |
| ELISA | 1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide: SSSIYDYDYLDDMTILVCRKDEVLSFGRC, corresponding to amino acids 18–45 of Mouse beta Chemokine Receptor D6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2071763 |
Product Specific Information
- Recommended positive controls: Mouse spleen cells and lung
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a beta chemokine receptor, predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to inflammation sites.
The gene is expressed in a range of tissues and hemopoietic cells. Expression in lymphatic endothelial cells and overexpression in vascular tumors suggest its role in chemokine-driven leukocyte recirculation and potential involvement in vascular tumor development.
This receptor binds most beta-chemokine family members, though its specific function remains unknown. The gene is mapped to chromosome 3p21.3, within a cluster of chemokine receptor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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