Thermo Fisher Scientific MCM2 Monoclonal Antibody (OTI8A11), TrueMAB
Human MCM2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 IHC(P)에서 사용 가능. Lyophilized 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. DNA 복제 조절 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A11 |
| Immunogen | Full length human recombinant protein of human MCM2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication.
MCM2, also known as CDCL1, mitotin, and BM28, is a human nuclear protein crucial for the onset of DNA replication and cell division.
It belongs to the family of early S-phase proteins and is mapped to chromosome 3q21.
CDCL1 is a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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