Thermo Fisher Scientific Phospho-GluR1 (Thr856) Polyclonal Antibody
GluR1 단백질의 Thr856 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Glutamate Receptor 1 around the phosphorylation site of Thr856 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GluR1 (Glutamate Receptor 1) is an ionotropic glutamate receptor.
L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Binding of L-glutamate induces a conformational change that opens the cation channel, converting a chemical signal into an electrical impulse.
The receptor then rapidly desensitizes and enters a transient inactive state characterized by a bound agonist.
In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization, characterized by delayed accumulation of current flux upon continued glutamate application.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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