
Thermo Fisher Scientific Glutaredoxin 2 Polyclonal Antibody
Thermo Fisher Scientific의 Glutaredoxin 2 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고순도 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Glutaredoxin 2 (amino acids 101–164) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs are part of the glutaredoxin system, which includes NADPH, GSH, and glutathione reductase, transferring electrons from NADPH to glutaredoxins via GSH.
Originally discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase reactions through two redox-active cysteine residues.
The active motif (Cys-Pro-Tyr-Cys) is conserved across species. This 12-kDa dithiol protein plays a crucial role in reducing mixed disulfides in cells under oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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