Thermo Fisher Scientific Aquaporin 4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Aquaporin 4 (AQP4), validated for Western blot applications. Recognizes membrane-localized, multi-pass water channel protein. Supplied as unconjugated liquid at 3.87 mg/mL, stored at -20°C. For research use only.
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Thermo Fisher Scientific Aquaporin 4 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 244–323 of human Aquaporin-4 (AQP4) (NP_001641.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.87 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913814 |
Product Specific Information
- Positive test controls: A-549, SKOV3
- Localization: Membrane, multi-pass membrane protein
- Immunogen sequence:
AGGLYEYVFC PDVEFKRRFK EAFSKAAQQT KGSYMEVEDN RSQVETDDLI LKPGVVHVID VDRGEEKKGK DQSGEVLSSV
Target Information
Aquaporin 4 (AQP4), also known as mercurial-insensitive water channel, localizes to the sarcolemma of fast-twitch skeletal muscle fibers. Aquaporins (AQPs) form a large family of integral membrane proteins facilitating water transport across cell membranes. This function is conserved across animals, plants, and bacteria. Multiple isoforms (AQP0–AQP10) exist in mammals, often co-expressed in the same cell. While most AQPs are selective for water, AQP3, AQP7, AQP9, and one AQP10 transcript also transport urea and glycerol.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(Aquaporin 4 Antigen Representation: PA5-120242_Aquaporin_4_P55087-1_Rabbit.svg 및 PA5-120242_Aquaporin_4_P55087-1_Rabbit_PDP.jpeg)
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