Thermo Fisher Scientific MTSS1 Polyclonal Antibody
Thermo Fisher Scientific의 MTSS1 폴리클로날 항체는 Human, Mouse, Rat 시료에 반응하며 Western blot과 ELISA에 적합합니다. Recombinant MTSS1(aa 630-730)을 면역원으로 사용한 Rabbit IgG 항체로, 액상 형태이며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MTSS1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 630–730 of human MTSS1 (NP_055566.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901166 |
Product Specific Information
- Positive Samples: HeLa, HT-29, U-87MG, Mouse liver, Mouse brain, Mouse heart, Rat liver
- Immunogen Sequence:
LPAPPDGPEE RGEHSPESPS VGEGPQGVTS MPSSMWSGQA SVNPPLPGPK PSIPEEHRQA IPESEAEDQE REPPSATVSP GQIPESDPAD LSPRDTPQGE D
Target Information
Metastasis suppressor protein 1 (MTSS1), also known as “missing in metastasis (MIM)”, was first identified as missing transcripts in metastatic bladder and prostate cancer cells.
MTSS1 is a 755-amino-acid multidomain scaffolding protein with proline-rich/SH3 binding and serine-rich regions containing EGF or PDGF/Src consensus sites.
It features an actin-binding Wiskott-Aldrich syndrome protein homology-2 (WH2) motif at the C-terminus and an N-terminal IMD domain that interacts with membranes and bundles actin filaments.
MTSS1 interacts with cortactin and enhances cortactin- and Arp2/3-dependent actin polymerization, contributing to cell motility and morphogenesis.
It also plays a role in sonic hedgehog/Gli signaling and is expressed in various tissues including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 원본은 본문 하단에 위치합니다)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.