Thermo Fisher Scientific IGHG1 Polyclonal Antibody
Thermo Fisher Scientific IGHG1 Polyclonal Antibody는 인간 IgG1 중심 영역을 인식하는 토끼 유래 폴리클로날 항체로, Western blot, IHC, ELISA 등에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 높은 순도(>95%)를 제공합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | - |
| ELISA | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG1 |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IgG1 (UniProt ID: P01857-2, range: 181–280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719156 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.
In the recognition phase of humoral immunity, membrane-bound immunoglobulins serve as receptors that, upon antigen binding, trigger clonal expansion and differentiation of B lymphocytes into plasma cells secreting immunoglobulins.
Secreted immunoglobulins mediate the effector phase of humoral immunity, eliminating bound antigens (PubMed:22158414, PubMed:20176268).
Each immunoglobulin has two antigen binding sites formed by variable domains of heavy and light chains.
Variable domains are assembled through V-(D)-J rearrangement and undergo somatic hypermutations, enabling affinity maturation after antigen exposure (PubMed:17576170, PubMed:20176268).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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