Thermo Fisher Scientific KHDC1 Polyclonal Antibody
KHDC1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC에 사용 가능. 인체, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 냉장 또는 냉동 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human KHDC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551925 |
Product Specific Information
- Suggested positive control: rat liver tissue lysate
- PA5-34573 can be used with blocking peptide PEP-1616.
Target Information
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins involved in various aspects of RNA metabolism, including transcription, splicing, transport, translation, and stability.
KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs.
KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway. The C-terminal putative transmembrane motif (TMM) is critical for its activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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