Thermo Fisher Scientific POLE3/CHRAC17 Monoclonal Antibody (PCRP-POLE3-3D3)
Thermo Fisher Scientific의 POLE3/CHRAC17 단클론 항체(PCRP-POLE3-3D3)는 인간 POLE3 단백질을 인식하며 ICC/IF, Flow Cytometry, ELISA, IP 등 다양한 응용에 적합합니다. 단일클론 Mouse IgG2a 형식으로, 200 µg/mL 농도의 액상 제품이며 Protein A/G로 정제되었습니다.
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Thermo Fisher Scientific POLE3/CHRAC17 Monoclonal Antibody (PCRP-POLE3-3D3)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/500 µg lysate |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-POLE3-3D3 |
| Immunogen | Recombinant full-length human POLE3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Mouse, Rat, Xenopus.
Target Information
Mitochondrial creatine kinase (MtCK) facilitates the transfer of high-energy phosphate from mitochondria to cytosolic creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. MtCK forms both dimers and octamers, unlike cytosolic isoenzymes that form only dimers. Sarcomeric MtCK shares 80% homology with ubiquitous MtCK coding exons. This gene includes motifs common to nuclear genes encoding mitochondrial proteins, suggesting a role in coordinated mitochondrial gene activation. Three transcript variants encoding the same protein have been identified.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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