Thermo Fisher Scientific Bmf Polyclonal Antibody
Rabbit polyclonal antibody targeting human Bmf protein. Validated for Western blot and immunocytochemistry applications. Supplied unconjugated in liquid form at 1 mg/mL concentration. Recommended positive controls include HepG2 or 293 cell lysates. For...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide EPSQCVEELEDDV, corresponding to amino acids 2–14 of Human Bmf |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2243537 |
Product Specific Information
- Recommended positive controls: HepG2 or 293 cell lysate
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. This protein contains a single BCL2 homology domain 3 (BH3) and has been shown to bind BCL2 proteins, functioning as an apoptotic activator. It is sequestered to myosin V motors by association with dynein light chain 2, potentially important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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