Thermo Fisher Scientific ABCA7 Polyclonal Antibody
ABCA7 단백질을 인식하는 Thermo Fisher Scientific의 다클론성 항체로, 마우스 시료에 반응합니다. Western blot 및 IHC에 사용 가능하며, ABCA7 특이적 결합을 제공합니다. 동결건조 형태로 제공되며, 연구용으로만 사용됩니다.
- 카탈로그번호
- OSA00198W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 2100–2155 of mouse ABCA7 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide shares about 93% identity with rat sequence.
- Specificity: ABCA7.
Target Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to transport various molecules across cell membranes. They are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of multiple membrane-spanning domains plus the Walker motifs for ATP interaction.
ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. High expression levels of ABCA7 in peripheral leukocytes, thymus, spleen, and bone marrow suggest a role in immune system lipid homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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