Thermo Fisher Scientific Phospho-MCM2 (Ser27) Polyclonal Antibody
Phospho-MCM2 (Ser27) Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 Ser27에 인산화된 MCM2 단백질을 특이적으로 검출합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 정제된 rabbit IgG 형태로 제공됩니다. DNA 복제 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCM2 (Accession P49736), corresponding to amino acid residues around phosphorylated Ser27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817584 |
Product Specific Information
This antibody detects endogenous levels of MCM2 only when phosphorylated at Ser27.
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin, and BM28) is a human nuclear protein crucial in the cell cycle, participating in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21 and has been considered a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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