Thermo Fisher Scientific LEF1 Recombinant Rabbit Monoclonal Antibody (ARC1019)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1019

Immunogen

Recombinant protein for a sequence within amino acids 50-150 of human LEF1 (Q9UJU2) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LEF1,uniProtId:Q9UJU2-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:399,antigenImageFileName:MA5-35521_LEF1_Q9UJU2-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35521_LEF1_Q9UJU2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849421

Product Specific Information

Immunogen sequence: LADIKSSLVN ESEIIPASNG HEVARQAQTS QEPYHDKARE HPDDGKHPDG GLYNKGPSYS SYSGYIMMPN MNNDPYMSNG SLSPPIPRTS NKVPVVQPSH A

Target Information

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.