Thermo Fisher Scientific IL-4 Monoclonal Antibody (BVD4-1D11)
인간 및 마우스 IL-4 단백질을 인식하는 Rat IgG2b 단일클론 항체. IHC(P) 및 유세포분석에 적합하며, 비결합형 액상 포맷으로 제공. 단기 보관은 4°C, 장기 보관은 -20°C 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BVD4-1D11 |
| Immunogen | Recombinant protein of human Interleukin 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Natural killer T cells
- Cellular Location: Secreted
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the interleukin 4 receptor. IL-4 exhibits a broad range of biological actions. The IL-4 receptor also binds to IL-13, contributing to overlapping cytokine functions. STAT6 is a key transcription factor mediating IL-4 signaling. The IL-4 gene, along with IL-3, IL-5, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5q, with IL-4 located near IL-13. These genes are regulated by long-range elements spanning approximately 120 kilobases. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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