Thermo Fisher Scientific Telomerase catalytic subunit Polyclonal Antibody
hTERT 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. WB, IHC, ICC/IF, ELISA, IP 등 다양한 응용 가능. Affinity chromatography로 정제된 액상 항체이며, -20°C 보관 권장. 연구용 전용 제품.
- 카탈로그번호
- 600-401-252x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Telomerase catalytic subunit Polyclonal Antibody
Thermo Fisher Scientific Telomerase Catalytic Subunit Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
| ELISA | 1:10,000–1:50,000 |
| Immunoprecipitation (IP) | 2 µL/mg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to a region near the carboxy terminal end of hTERT (accession number AF018167). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
- Reported to react with mouse TERT (mTERT), though binding is weaker and less specific than to hTERT.
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by adding the repeat sequence TTAGGG. It consists of a protein component with reverse transcriptase activity (TERT) and an RNA component serving as a template. Telomerase expression is typically repressed in postnatal somatic cells, leading to telomere shortening and cellular senescence. Deregulation of telomerase may contribute to oncogenesis. In mice, telomerase may also aid chromosomal repair via de novo synthesis of telomere repeats. Multiple alternatively spliced variants of TERT have been identified, with some full-length sequences undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일은 본문 하단에 배치됩니다.)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.