Thermo Fisher Scientific Phospho-mTOR (Ser2448) Recombinant Rabbit Monoclonal Antibody (mTORS2448-E11), APC
APC 형광으로 표지된 인산화 mTOR(Ser2448) 특이 재조합 토끼 단클론 항체. 인간 및 생쥐 시료에 반응하며, Flow Cytometry에 적합. 세포 성장 및 암 관련 mTOR 신호 연구에 유용. Protein A/G 정제, PBS+BSA buffer, 4°C 보관.
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Applications
- Flow Cytometry (Flow): Tested dilution 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | mTORS2448-E11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897081 |
Additional Formats
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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