Thermo Fisher Scientific EPM2A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human EPM2A. Recombinant protein control fragment (Product #RP-91068).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856784

Product Specific Information

Immunogen sequence: ATGHTNEMKH TTDFYFNIAG HQAMHYSRIL PNIWLGSCPR QVEHVTIKLK HELGITAVMN FQTEWDIVQN SSGCNRYPEP MTPDTMIKLY REEGLAYIWM PTPDMSTEGR VQMLP

Target Information

The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.