Thermo Fisher Scientific TIAF1 Polyclonal Antibody
TIAF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능하며, 인간과 생쥐 시료에 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TIAF1 (Accession O95411), corresponding to amino acid residues N80–G115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852813 |
Product Specific Information
Antibody detects endogenous levels of total TIAF1.
Target Information
TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD, and FADD.
It localizes to the nucleus and is significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection.
Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation.
TIAF1 is essential in p53- and WOX1-mediated cell death and shows aggregation-dependent control of tumor progression, metastasis, and regulation of cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-103477_TIAF1_O95411-1_Rabbit.svg)
(이미지: PA5-103477_TIAF1_O95411-1_Rabbit_PDP.jpeg)
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