Thermo Fisher Scientific GPR132 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

12 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 18 amino acid peptide from C-terminus of human GPR132 / G2A. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR132,uniProtId:Q9UNW8-1,ncbiNodeId:9606,antigenRange:380,antigenLength:380,antigenImageFileName:PA5-32797_GPR132_Q9UNW8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-32797_GPR132_Q9UNW8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550259

Product Specific Information

Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Marmoset (89%); Gibbon, Monkey (83%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.