Thermo Fisher Scientific B4GALT1 Polyclonal Antibody
Thermo Fisher Scientific의 B4GALT1 Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도 Affinity chromatography 정제 및 안정적 액상 형태로 제공됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific B4GALT1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human B4GALT1 (Accession P15291), corresponding to amino acid residues L321–L371 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854285 |
Product Specific Information
Antibody detects endogenous levels of total B4GALT1.
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have specificity for the donor substrate UDP-galactose, transferring galactose in a beta1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl.
Each beta4GalT has distinct functions in the biosynthesis of glycoconjugates and saccharide structures.
As type II membrane proteins, they possess an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and serves as a transmembrane anchor.
By sequence similarity, the beta4GalTs form four groups:
- beta4GalT1 and beta4GalT2
- beta4GalT3 and beta4GalT4
- beta4GalT5 and beta4GalT6
- beta4GalT7
This gene is unique among the beta4GalT genes as it encodes an enzyme involved in both glycoconjugate and lactose biosynthesis.
In lactating mammary tissues, the enzyme forms a heterodimer with alpha-lactalbumin to catalyze the reaction:
UDP-galactose + D-glucose ⇔ UDP + lactose.
The two enzymatic forms result from alternate transcription initiation sites and post-translational processing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.