Thermo Fisher Scientific TSG Polyclonal Antibody
TSG 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot 및 IHC(Frozen) 적용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품으로, PBS와 trehalose 버퍼에 보관. 연구용 전용 시약.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant mouse TSG (Cys25–Phe222) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605579 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
TWSG1 may be involved in dorsoventral axis formation. It antagonizes BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to its anti-BMP function, it also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. TWSG1 may play an important role in BMP-regulated cartilage development, chondrocyte differentiation, and thymocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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