Thermo Fisher Scientific MLK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MAP3K10. Recombinant protein control fragment (Product #RP-89758). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MLK2,uniProtId:Q02779-1,ncbiNodeId:9606,antigenRange:476-589,antigenLength:954,antigenImageFileName:PA5-82276_MLK2_Q02779-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82276_MLK2_Q02779-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789435

Product Specific Information

Immunogen sequence: LPSGFEHKIT VQASPTLDKR KGSDGASPPA SPSIIPRLRA IRLTPVDCGG SSSGSSSGGS GTWSRGGPPK KEELVGGKKK GRTWGPSSTL QKERVGGEER LKGLGEGSKQ WSSS

Target Information

MAP3K10 (MLK2) is a serine/threonine kinase which has been shown to activate MAPK8/JNK and MKK4/SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.