Thermo Fisher Scientific PLAU Monoclonal Antibody (OTI1D4), TrueMAB
인간 PLAU 단백질(아미노산 107–379)을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상형 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 저장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 107–379 of human PLAU produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA), which can be further processed into LMW-uPA. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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