Thermo Fisher Scientific Human LRFN1 Synthetic Peptide
인간 LRFN1 단백질의 C-말단 18 아미노산 서열 기반 합성 펩타이드. PA5-20698 항체의 블로킹 펩타이드로 사용 가능. 신경 조직에서 발현되는 LRFN 단백질 연구에 적합. 연구용으로만 사용.
- 카탈로그번호
- PEP0813
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human LRFN1.
PEP-0813 can be used as a blocking peptide with polyclonal antibody PA5-20698.
Target Information
LRFN1 is a member of a family of five transmembrane glycoproteins highly expressed in neuronal tissues.
LRFN proteins share a leucine-rich repeat (LRR)–immunoglobulin-like (Ig)–fibronectin type III (Fn)–transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family.
Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.
LRFN1, -2, and -4 bind to PDZ domains of postsynaptic PSD95, redistributing PSD95 to the cell periphery.
It has been suggested that Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
At least two isoforms of LRFN1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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