Thermo Fisher Scientific Human FNIP2 Synthetic Peptide
Human FNIP2 단백질의 N-말단 18개 아미노산 서열을 기반으로 한 합성 펩타이드. FNIP2 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태, PBS(pH 7.2)와 0.1% BSA 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human FNIP2.
PEP-0806 can be used as a blocking peptide with polyclonal antibody PA5-20691.
Target Information
FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin acts as a tumor suppressor, as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1 (sharing 49% identity with FNIP2) bind to AMPK, an important energy sensor that negatively regulates mTOR, a key regulator of cell growth and proliferation. FNIP1 and FNIP2 can form homo- and heteromeric multimers, suggesting functional interaction between these proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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