Thermo Fisher Scientific MB67 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human MB67 protein; validated for WB and IHC(P) applications. Detects endogenous 35 kDa protein with >95% purity. Supplied as 1 mg/mL liquid, unconjugated form; storage at 4°C or -20°C recommended.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 70–124 of human MB67 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553448 |
Product Specific Information
- Detects endogenous MB67 protein at a molecular weight of 35 kDa.
- Purity >95% by SDS-PAGE.
Target Information
This gene encodes a member of the nuclear receptor superfamily and acts as a key regulator of xenobiotic and endobiotic metabolism. The protein binds DNA as a monomer or as a heterodimer with the retinoid X receptor, regulating transcription of genes involved in drug metabolism and bilirubin clearance (e.g., cytochrome P450 family). Unlike most nuclear receptors, it is constitutively active in the absence of ligand but can be modulated by agonists and inverse agonists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-36268_MB67_Q14994-1_Rabbit_PDP.jpeg)
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