Thermo Fisher Scientific FOXO4 Recombinant Rabbit Monoclonal Antibody (23GB1470)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA553994 | - | Thermo Fisher Scientific MA553994 FOXO4 Recombinant Rabbit Monoclonal Antibody (23GB1470) 100 uL pk | 재고문의 | pk | 0원 | - | 0원 | ||
MA553995 | - | Thermo Fisher Scientific MA553995 FOXO4 Recombinant Rabbit Monoclonal Antibody (23GB1470) 20 uL pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:5,000
Immunocytochemistry (ICC/IF)
1:1,000
Flow Cytometry (Flow)
1:2,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB1470
Immunogen
A synthesized peptide derived from human FoxO4 (450-505AA). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
FOXO4,
uniProtId:
P98177-1,
ncbiNodeId:
9606,
antigenRange:
450-505,
antigenLength:
505,
antigenImageFileName:
MA5-53994_FOXO4_P98177-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-53994_FOXO4_P98177-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
FOXO4 (Forkhead box O4) is encoded by the FOXO4 gene located on the X chromosome. It is also known as AFX1 or MLLT7 (Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Translocated To, 7) and is a member of the O class of forkhead/ winged helix family of transcription factors along with FOXO1, FOXO3 and FOXO6. FOXO4 is abundantly expressed in skeletal muscle and adipose tissue. FOXO4 binds to the Insulin Responsive Element (IRE) and activates downstream targets of Insulin/IGF1 signaling such as IGFBP1. However, the activation of another downstream target of the Insulin/IGF1 pathway, Akt, leads to phosphorylation of FOXO4 on specific Ser/Thr residues. This phosphorylation mediates binding of FOXO4 to 14-3-3 and eventual exit of FOXO4 from the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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