Thermo Fisher Scientific DLAT Recombinant Rabbit Monoclonal Antibody (23GB1010)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA553986 | - | Thermo Fisher Scientific MA553986 DLAT Recombinant Rabbit Monoclonal Antibody (23GB1010) 100 uL pk | 재고문의 | pk | 0원 | - | 0원 | ||
MA553987 | - | Thermo Fisher Scientific MA553987 DLAT Recombinant Rabbit Monoclonal Antibody (23GB1010) 20 uL pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:5,000
Immunocytochemistry (ICC/IF)
1:1,000
Flow Cytometry (Flow)
1:2,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB1010
Immunogen
A synthetic peptide of human Pyruvate Dehydrogenase E2 (594-608AA). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
DLAT,
uniProtId:
P10515-1,
ncbiNodeId:
9606,
antigenRange:
594-608,
antigenLength:
647,
antigenImageFileName:
MA5-53986_DLAT_P10515-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-53986_DLAT_P10515-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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