Thermo Fisher Scientific TWIST1 Recombinant Superclonal Antibody
TWIST1 단백질을 인식하는 Thermo Fisher Scientific의 Recombinant Superclonal 항체로, 인간 및 다양한 종에 반응합니다. 고감도·고특이성을 제공하며, WB 및 ICC/IF에 적합합니다. 재조합 기술로 로트 간 일관성과 높은 재현성을 보장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to human TWIST1 (aa1–aa100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2688313 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, Horse, and Mouse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, and providing consistent performance across lots.
While they function similarly to polyclonal antibodies—recognizing multiple epitopes and offering high sensitivity—they are produced from a defined mixture of light and heavy chains, eliminating biological variability.
Formerly called “Recombinant polyclonal antibody,” this product is now rebranded as “Recombinant Superclonal™ antibody.” The physical product and performance remain unchanged.
Target Information
TWIST1 acts as a transcriptional regulator. It inhibits myogenesis by sequestering E proteins, blocking trans-activation by MEF2, and preventing DNA-binding by MYOD1 through physical interaction.
TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B, and regulates cranial suture patterning and fusion depending on dimer composition.
Mutations in TWIST1 are implicated in Saethre-Chotzen syndrome, characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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