Thermo Fisher Scientific TRAPPC5 Polyclonal Antibody

Thermo Fisher Scientific TRAPPC5 Polyclonal Antibody

Applications and Tested Dilution

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
AVWKALFGKEA DKLEQANDDA RTFYIIEREP LINTYISVPK ENSTLNCASF TAGIVEAVLT HSGFPAKVTA HWHKGTTLMI KFEEAVIARD R

Highest antigen sequence identity to the following orthologs:

• Mouse: 100%
• Rat: 100%

Target Information

TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily.
Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor.
Evolutionarily conserved, TRAPPC5 plays a role in protein binding, vesicle-mediated transport, and nucleotide exchange stimulation.
It performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo, localizing to the Golgi apparatus and is essential for ER-to-Golgi and intra-Golgi vesicle trafficking.
In mammals, TRAPPC5 is also involved in post-Golgi trafficking.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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