
Thermo Fisher Scientific Ksp-Cadherin (Kidney-Specific Cadherin) Polyclonal Antibody
Kidney-specific cadherin(CDH16)을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 고순도 Protein A 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human CDH16 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cadherins are a family of Ca²⁺-dependent adhesion molecules that mediate cell-cell binding, crucial for structural maintenance and morphogenesis. Each cadherin has a large extracellular domain at the N-terminus composed of five homologous repeats, with the distal repeat conferring binding specificity.
Cadherin-16 (Ksp-Cadherin) is a type I membrane protein expressed specifically in the kidney, localized to the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21–proximal 16q22, while the mouse gene is found in a syntenic region of distal chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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