Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI2E1), TrueMAB
PCDHGC5 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot 및 IHC(P) 검증됨. 인간 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a unique regulatory and expression mechanism.
The gamma gene cluster includes 22 genes divided into 3 subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region (6 cadherin ectodomains and a transmembrane region), while the constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins likely play a crucial role in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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