
Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI2G2), TrueMAB
인간 PCDHGC5 단백질에 특이적인 단일클론 항체로 Western blot에 최적화됨. 마우스 IgG1 아이소타입이며 액상 형태로 제공. 친화 크로마토그래피로 정제되어 높은 순도 보장. 연구용으로 세포 간 접착 단백질 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PCDHGC5 gene belongs to the protocadherin gamma gene cluster, one of three related clusters located on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a unique regulatory mechanism. The gamma cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while constant region exons encode the shared cytoplasmic region. These neural cadherin-like proteins are believed to play critical roles in establishing and maintaining specific cell–cell connections in the brain. Alternative splicing has been observed among the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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