Thermo Fisher Scientific KCNH1 Polyclonal Antibody
KCNH1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNH1 (Accession O95259), corresponding to amino acid residues S819–S869 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851198 |
Product Specific Information
Antibody detects endogenous levels of total KCNH1.
Target Information
Voltage-gated potassium (Kv) channels are a complex class of voltage-gated ion channels involved in diverse physiological processes, including neurotransmitter release, heart rate regulation, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume control.
KCNH1 encodes a member of the voltage-gated potassium channel subfamily H, functioning as a pore-forming (alpha) subunit of a non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation and is highly expressed in brain and myoblasts. Overexpression of KCNH1 may confer a growth advantage to cancer cells and promote tumor proliferation. Alternative splicing results in two transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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