Thermo Fisher Scientific Serglycin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Serglycin. Recombinant protein control fragment (Product #RP-93682). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Serglycin,uniProtId:P10124-1,ncbiNodeId:9606,antigenRange:2-125,antigenLength:158,antigenImageFileName:PA5-51452_Serglycin_P10124-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51452_Serglycin_P10124-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647139

Product Specific Information

Immunogen sequence: MQKLLKCSRL VLALALILVL ESSVQGYPTR RARYQWVRCN PDSNSANCLE EKGPMFELLP GESNKIPRLR TDLFPKTRIQ DLNRIFPLSE DYSGSGFGSG SGSGSGSGSG FLTEMEQDYQ LVDE

Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 55%.

Target Information

This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.