Thermo Fisher Scientific UPRT Polyclonal Antibody
Human UPRT 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 핵 및 세포질 내 UPRT 단백질 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UPRT. Recombinant protein control fragment (Product #RP-91918). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649298 |
Product Specific Information
Immunogen sequence:
TGYKYEGVKF EKGNCGVSIM RSGEAMEQGL RDCCRSIRIG KILIQSDEET QRAKVYYAKF PPDIYRRKVL LMYPILSTGN TVIEAVKVLI EHGVQPSVII LLSLFSTPHG AKSIIQEFPE IT
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP).
This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway.
The enzyme localizes to the nucleus and cytoplasm.
The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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